Daily Archives: May 15, 2015


A clinical trial of low-dose methotrexate on inflammation in HIV-infected people who are at risk for cardiovascular disease (CVD): A5314. https://actgnetwork.org/study/a5314-mtx-hiv-positives Brief Summary and Purpose of this study: Anti-HIV medicines have been very successful in allowing people with HIV to control the virus. However, researchers have noticed that many patients have […]

A5314: Effects of methotrexate on inflammation in poz folks at ...


A Phase 2B clinical trial to evaluate the safety and drug levels of a human monoclonal antibody (VRC01) administered in multiple doses intravenously and subcutaneously in different dosing schedules to healthy, HIV-uninfected adults. This strategy is called passive immunization, or antibody-mediated prevention (AMP).   Purpose of the Study Primary objective 1: To evaluate the […]

AMP Study: A Passive Immunization Clinical Trial for HIV-Negative Adults