Brooke Willis


Gilead Sciences awards $2.5 million to CWRU AIDS Clinical Trials Unit February 1, 2017: Gilead Sciences awarded CWRU School of Medicine’s Michael M. Lederman, MD to study HIV Reservoir Reduction with Interleukin-2 and monoclonal antibody treatments. IL-2 and certain monoclonal antibodies have been shown separately to reduce the presence of HIV, […]

Lederman gets $2.5M Gilead grant to study one-two punch


HVTN116 The Case Western Reserve Clinical Trials Unit is currently enrolling healthy, HIV-negative women and men, ages 18-50, in an HIV prevention vaccine trial, sponsored by the National Institutes of Health.  The study is enrolling 101 participants in 5 cities.  This trial is not asking whether the vaccines work as […]

Vaccine Study Enrolling HIV-Negative Men & Women



Over $22M in Grants from Gilead to Study HIV Cure Research January 11, 2017: Gilead awards over $22 million to a dozen HIV cure research projects. Case Western Reserve University School of Medicine’s Michael M. Lederman, MD to study Reservoir Reduction with Interleukin-2 and Transcriptional Activation. https://www.poz.com/article/22m-grants-gilead-study-three-areas-hiv-cure-research  

Gilead funds CWRU cure research


 Protocol Summary:  This is a phase IV randomized, double-blinded, placebo-controlled study to assess the efficacy of adding maraviroc (MVC) and dolutegravir (DTG) to the current antiretroviral therapy (ART) of HIV-infected individuals who have at least mild neurocognitive impairment with a primary outcome of improvement in neurocognitive performance. Purpose of This […]

A5324: To see if adding extra anti-HIV medicines reduces HIV-associated ...



HIV is not a crime
Ohio Supreme Court Will Review Felony HIV Exposure Law & Conviction October 5, 2016: The Center for HIV Law and Policy and the ACLU of Ohio Foundation submitted a brief supporting the petition for Ohio Supreme Court review of State of Ohio v. Orlando Batista, arguing that Ohio’s felonious assault […]

HIV Is Not a Crime


Mort Mandel commits $100,000 for outstanding chemistry faculty award Yet again, Mandel has chosen to live his principles in his charitable giving. Through the Morton and Barbara Mandel Family Foundation, he committed $100,000 for the Morton L. Mandel Award endowment. The annual award will honor and reward outstanding faculty members […]

Blanton Tolbert awarded inaugural Mandel endowment






Links to protocol summaries of current & upcoming clinical trials at the Case site Case ACTU Protocols December 2016 A5324: The effect of ART intensification of Maraviroc and Dolutegravir on HIV-related cognitive impairment A5332 The REPRIEVE trial: The effect of pitavastatin on preventing vascular events in HIV A5336: The effect […]

Protocol Summaries







Special Immunology Unit director and PrEP Clinic founder Barbara Gripshover, MD http://medicine.case.edu/department-newsletter/february-2016-newsletter Barbara Gripshover, MD, Medical Director of the John T. Carey Special Immunology Unit (SIU) at University Hospitals Case Medical Center, and founder of the area’s first PrEP Clinic, examines common barriers to engaging patients with HIV in health […]

Barbara Gripshover, SIU director


School of Nursing’s Allison Webel contributes to 4th edition http://thedaily.case.edu/news/as-hiv-patients-live-longer-updated-guide-helps-patients-navigate-new-territory/ The Case Daily reports that Frances Payne Bolton School of Nursing professor and HIV researcher Allison Webel is part of a team that has updated a patient guide for HIV care, treatment and how to communicate with family, friends and others about […]

HIV Book Updated by CWRU’s Allison Webel






Inaugural appointment The CWRU School of Medicine advances its legacy of HIV research innovation and collaboration by bringing on Rafick-Pierre Sékaly, PhD, one of the world’s leading scientists in AIDS research, human immunology and immunotherapy, as the inaugural Richard J. Fasenmyer Professor of Immunopathogenesis. Read more at http://thedaily.case.edu/news/?p=41184 More information about the Fasenmyer […]

Leading AIDS researcher appointed to Fasenmyer Professorship in School of ...